Alpha Arbutin

Product Description

Appearance: White powder
CAS: 84380-01-8
Specificcation:≥99.5%   HPLC

Hydroquinone:Negative

Melting Point:203-206（±1）℃

Specific Optical Rotation:[a]20D= + 174.0°- +186.0°

Solubility:Soluble in water, slightly soluble in ethanol

Clarity:Solution should be clarify, none suspended matters

Alpha Arbutin is enzymatically synthesized from hydroquinone and saccharides through transglycosylation reaction. Various carbohydrate-active enzymes

Application

1.Skin whitening

Arbutin exhibits potent melanin-inhibiting properties and confers whitening effects on the skin. Sun damage and injury or inflammation to the skin from acne, eczema or psoriasis are the two main factors that cause melanin production on the skin. Arbutin can reduce the accumulation of pigment by inhibiting the production of melanin, which accumulates on the skin when tyrosine is oxidized. An enzyme called tyrosinase is the catalytic for this reaction. Scientists found arbutin has shown inhibitory actions against tyrosinase. When topically apply skincare products containing Arbutin, the inhabitation of tyrosinase results in the decrease of melanin, thus, a whiter complexion. 

Hyperpigmentation in the epidermis is caused by excessive melanin synthesis due to UV irradiation, wound or stress. Tyrosinase is one of the key enzymes involved in melanin synthesis. The enzyme catalyses the first two steps in melanin synthesis: the hydroxylation of tyrosine to DOPA and the oxidation of DOPA to dopaquinone. Arbutin has an direct inhibitory function against tyrosinase, which leads to the prevention of melanin formation and a whitening effect on the skin.

2.Alpha-Arbutin V.S. Beta-Arbutin

Recent research showed that Alpha-Arbutin has a 10-fold stronger inhibitory effect on the activity of tyrosinase from human malignant melanoma cells than that of Beta-Arbutin. The α-glucosidic bond found in Alpha-Arbutin offers higher stability than the β form found in the related Beta-Arbutin. Moreover, Alpha-Arbutin hardly inhibited cell growth at 1 mmol/L, while Beta-Arbutin inhibit it significantly at the same concentration. It is, therefore, considered that Alpha-Arbutin is an effective and safe ingredient for cosmetics. Alpha arbutin is very expensive. That is the one downside.

3.Arbutin Application and Dosage

Arbutin is used as a skin whitening agent, a sunscreen agent and an antioxidant in cosmetic formulations. Arbutin soap, cream, serum and lotion are among the major lightening products you will found in the market.

Eyes Gel Strip Masks

Beauty Facial Mask

Arbutin Mask sheet

Skin Lightening Serum

Skin Whitening Peel Pads

4.Arbutin's Advantage Over Traditional Skin-whitening Products

Arbutin can inhibit melanogenesis without causing melanocyte toxicity, unlike traditional depigmenting agents such as hydroquinone, corticosteroids, and kojic acid.

Function

This product can be used in health care products, food, cosmetics and other industries. This product has a variety of functions,due to policy changes, the function and application of some ingredients cannot be disclosed.

Note

Arbutin breaks down easily in acidic conditions, so the pH value of cosmetics containing Arbutin should be greater than 6.0.

Please dissolve arbutin in 50℃ hot water before adding it to skin whitening products. (Arbutin is soluble in hot water, methanol or alcohol. Arbutin is partially soluble in cold water. Arbutin is insoluble in aether, chloroform or benzene.)

Antioxidants should be added to cosmetics containing Arbutin.

Others

OEM,COA,HPLC,HALAL,Kosher and FREE sample can provide you

Arbutin compounding with vitamin C derivatives can make skin more moisturizing and transparent.

With hyaluronic acid can relieve dry skin;

With glycyrrhizic acid can repair sunburn.