Beijing Yuanzhi Biology Co.,Ltd.
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40% Glabridin HPLC
Product Description
Specification:
Product Name:Glabridin
CAS Number 59870-68-7
Specification 40% 90% 99%
Usage Cosmetic Raw Materials
Glabridin Cosmetic Skin Care Whitening Lightening Powder CAS 59870-68-7 Glabridin
Glabridin, also known as Glycyrrhizic Flavone, is an kind of isoflavone. It is extracted from the dried rhizome of Glycyrrhiza glabra L. Glabridin is one of the main flavonoids in Glycyrrhiza glabra (accounting for 11%). Yuanzhi Bio develops 2 different specifications of Glabridin: 90% white powder, 40% white powder. Numerous studies have shown that Glabridin can effectively inhibit the activity of various enzymes during melanin production, especially inhibiting tyrosinase activity. Moreover, it has other skin-care effect such as anti-inflammation, anti-oxidation and sun-protection. It is a safe, mild and effective whitening active ingredient. Only 100g Glabridin can be extracted from 1000kg Glycyrrhiza glabra. Because of its complicated extraction process, high cost and price, it is comparable to gold price. Therefore, it is known as “Whitening Gold” in the world cosmetics industry. Glabridin has attracted much attention and is widely used in skin beauty products and cosmetics.
Application
1. Skin whitening
As a natural whitening ingredient, the skin-whitening mechanism of Glabridin mainly includes:
(1) inhibiting tyrosinase activity;
(2) inhibiting the activity of dopachrome tautomerase (TRP-2)
(3) inhibiting the activity of DHICA oxidase;
(4) exerting the function of endothelin antagonist;
(5) increasing the total antioxidant capacity of the skin;
(6) effectively scavenging oxygen free radicals and its chain reaction. Moreover, through these synergistic effects, it effectively prevents the polymerization of 5,6-dihydroxyindole (DHI) and the production of dopachrome. Thereby Glabridin can disturb and hinder the formation and transport of melanin; and then it inhibits and reduces pigmentation so as to achieve whitening skin effect.
2. Anti-inflammatory and antibacterial
3. Antioxidant
4. Sunscreen
Others
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